SEMTA. Sociedad Española de Mecánica Teórica y Aplicada

Sociedad Española de
Mecánica Teórica y Aplicada

Previous Next

Mechanobiological Modelling of Bone Regeneration Processes

In silico as well as in vivo models of different complex bone regeneration processes (bone transport and bone lengthening) have been carried out to understand the mechanobiology of the distraction callus as well as to improve the clinical applications. 

In silico modelling aims to predict the time-varying tissue evolution during distraction osteogenesis using a Finite element framework. The reliability of the formulation has been tested in patient specific models confirming the huge potential of mechanobiological models on clinical procedures. 

In vivo modelling aims to relate quantifiable biological parameters (the bone tissue volume, proportion of different tissue types...) with mechanical parameters (the force through the fixator and through the callus, the mechanical properties of the callus tissue during the process, gait parameters,...) during the bone regeneration processes.

Attention! This site uses cookies and similar technologies. If you do not change the configuration of your browser and continue browsing our website, we understand that you accept its use.